Methyl-5-Deoxy-2,3-O-Isopropylidene-D-Ribofuranoside(Capacitabine Intermediate) - Names and Identifiers
Methyl-5-Deoxy-2,3-O-Isopropylidene-D-Ribofuranoside(Capacitabine Intermediate) - Physico-chemical Properties
Molecular Formula | C9H16O4
|
Molar Mass | 188.22 |
Density | 1.11±0.1 g/cm3(Predicted) |
Boling Point | 73-75 °C(Press: 12 Torr) |
Methyl-5-Deoxy-2,3-O-Isopropylidene-D-Ribofuranoside(Capacitabine Intermediate) - Introduction
Methyl-5-deoxy-2, is an organic compound whose chemical formula is C11H20O4.
Nature:
-Appearance: Colorless solid
-Melting point: 62-65°C
-Refractive index: 1.454
-Stability: stable at room temperature, but may decompose under high temperature and sunlight
Use:
-Chemical synthesis: As a substrate or reagent in organic synthesis, it is used to synthesize other organic compounds.
-Drug research: for the synthesis and research of antiviral, anti-tumor drugs.
Preparation Method:
The synthesis of Methyl-5-deoxy-2 can use a variety of methods. Common preparation methods include:
1. React 2,3-isopropyl-D-ribofuranoside with a methylating agent to generate methyl -2,3-O-isopropylidene-D-ribofuranoside, and then deoxygenate it.
2. React 2,3-O-isopropylidene-D-ribofuranose with a methylating reagent to generate methyl -2,3-O-isopropylidene-D-ribofuranose, which is then deoxygenated.
Safety Information:
Methyl-5-deoxy-2, the specific safety of the need for detailed testing and evaluation. In use, should follow the laboratory safety procedures, and pay attention to prevent contact with skin, eyes and inhalation. In case of accidental contact, rinse immediately with plenty of water and seek medical treatment. Store the compound in a sealed container away from heat and open flames.
Last Update:2024-04-09 02:00:48